Overview of Lipo-C Injection
Dosage StrengthMethionine / Inositol / Choline Chloride / L-Carnitine / Thiamine HCl / Dexpanthenol 15/50/50/50/15/5 mg/mL 10 mL Vial
Methionine / Inositol / Choline Chloride / L-Carnitine / Thiamine HCl / Dexpanthenol 15/50/50/50/15/5 mg/mL 30 mL Vial
A combination of substances in the Lipo-C injection may help reduce adipose tissue (fat). Although each chemical in the mixture might work well on its own, when combined, they might have greater lipotropic effects than when used singly. Because parenteral exposure has a higher bioavailability than oral supplementation, injecting this blend of lipotropic substances may be more beneficial.
These lipotropic substances either play a role in the homeostasis of energy synthesis from fat or have structural and functional similarities to the B-vitamins. While the MIC mixture and B vitamin(s) are frequently injected separately, they are still a part of the same general injection cycle because these chemicals are frequently used together in the goal of enhancing fat loss. The non-vitamin chemicals (MIC) injected into the body encourage the liver to optimize the metabolic process, increase the mobilization and use of fat, and provide the necessary metabolic environment for the body.
On the potential for the release of fat deposits in some body regions, lipotropic substances are used. They are also known as MIC Injection, Lipo-Den, Lipo-Plex, Lipo Shot, and similar terms. These lipotropic substances are contained in this injection:
Methionine supports the liver’s ability to handle fatty acids at their peak level.
1 S-adenosylmethionine, which has been linked to the genetic control and activation of a number of genes, contains a significant amount of methionine. 2 Methionine helps histones donate methyl, which activates specific genetic mechanisms that may be responsible for the rise in lean tissue. The increase in lean tissue is thought to enhance resting metabolic rate, which raises the total number of calories that must be gained from diet or storage, even if this is only indirectly related to lipolysis. Methionine has been proven in animal models to increase CNS activity, which in turn increases the amount of calories the CNS needs3 The subsequent ramifications of this can ultimately result in an increase in the total organism’s calorie needs. Nevertheless, studies have not been verified. Because organisms share many similar pathways, there might be a correlation in humans.
Inositol is a molecule that resembles sugar and is classified as a sugar alcohol. Despite having a chemical structure that is quite similar to glucose, this molecule does not have the characteristics of simple carbohydrates. It has been demonstrated that this sugar alcohol does not actively promote adipose storage, in contrast to simple carbs. In fact, it has been discovered that inositol reduces the activity of fatty acid synthase, a multi-enzyme protein that catalyzes fatty acid production. The body eventually uses this group of enzymes to generate triglycerides, which are fat molecules found in adipose tissue (body fat). 3
A frequent disease linked to increased adiposity, insulin resistance, may be effectively treated with inositol (body fat).
5 A condition known as insulin resistance occurs when your body becomes resistant to the actions of the hormone insulin. In addition to a variety of symptoms and dysfunctions, this illness causes elevated blood glucose levels. The body’s sensitivity to insulin signaling is known to be controlled by a substance known as inositol phosphoglycan. Because inositol is structurally incorporated into inositol phosphoglycan, inositol is necessary for this molecule to function as a regulator.
Most healthy people exhibit normal insulin sensitivity and function, which is crucial for preserving general health. Excessive blood glucose exposure eventually causes insulin resistance and inefficient food delivery. This condition may be improved by inositol although fatty acid (fat) synthesis is also decreased.
Simple molecule choline is typically categorized as a B vitamin. The B vitamin class often contributes to energy production and metabolism assistance. The neurotransmitter acetylcholine has a crucial precursor in choline. This neurotransmitter is involved in a variety of processes, including the contraction and operation of muscles. A crucial neurotransmitter that promotes communication between neurons is acetylcholine. Enhanced CNS activity and increased brain transmission ultimately result in increased energy use. Nutrient input is necessary for energy expenditure and might come from dietary nutrients or stored energy (fat). Together with methionine and folate, choline maintains a delicate equilibrium and homeostasis. Negative health impacts may be present when these nutrients are out of balance. According to many users, greater CNS activity is accompanied by improved cognitive function. As a nootropic, or a chemical with the capacity to enhance cognition, choline may be useful. Choline’s function as an acetylcholine precursor is assumed to be the cause of the improvement in neuronal cognition.
Choline supplementation has been proven to lower urine and serum carnitine levels.
4 Carnitine may have been partitioned in tissues that use it as a fatty acid mitochondrial transport if its concentration in these fluids has decreased. Fatty acids are transported by carnitine to the mitochondria, where they are broken down and converted to energy. Additionally, molecular pieces of fat have reportedly been discovered in urine following choline and carnitine administration. This finding may be the result of incomplete fatty acid oxidation and the elimination of the resulting byproducts. 4 This indicates that even while not all fatty acids are burned as energy, choline supplementation may boost the usage of carnitine and increase the elimination of fatty acids. The molecular fragments of fatty acid fragments that are not consumed as energy are excreted in the urine.
Choline, which accelerates the mobilization of fatty acids and prevents their accumulation in a specific area of the body, along with methionine, which aids the liver in maintaining its optimal capacity to handle fatty acids;
In addition, when combined with choline, inositol, which helps in the transfer of fat into and out of the liver and intestinal cells, has greater lipotropic effect than when used alone. 8
Once the effects of all six of these medications have worn off, the body gradually resumes its regular pace of fat and overall metabolism.
These medications are frequently taken together. The frequency of injections is up to twice per week. B12 is said to increase general metabolic rates and give users and practitioners a stronger sense of overall vitality and well-being. 9 Although the MIC mixture and B vitamin(s) are frequently injected separately, they are all a part of the same overall injection cycle because these lipotropics are structurally and functionally closely related to the B-vitamins, so they are frequently used together in the hope of amplifying the potential for fat-loss. The non-vitamin chemicals (MIC) injected into the body cause the liver to optimize metabolism, increase the movement and use of fat, and temporarily increase the body’s metabolic rate.
In an effort to intensify these effects even further, additional substances are included:
- Thiamine HCl (Vitamin B1)
- Dexpanthenol (Vitamin B5)
1.Best, C.H. and J.H. Ridout, The lipotropic action of methionine. J Physiol, 1940. 97(4): p. 489-94.
2.Jones, P.A. and D. Takai, The role of DNA methylation in mammalian epigenetics. Science, 2001. 293(5532): p. 1068-70.
3.Young, S.N. and M. Shalchi, The effect of methionine and S-adenosylmethionine on S-adenosylmethionine levels in the rat brain. J Psychiatry Neurosci, 2005. 30(1): p. 44-8.
4.Hongu, N. and D.S. Sachan, Carnitine and choline supplementation with exercise alter carnitine profiles, biochemical markers of fat metabolism and serum leptin concentration in healthy women. J Nutr, 2003. 133(1): p. 84-9.
5.Corrado, F., et al., The effect of myoinositol supplementation on insulin resistance in patients with gestational diabetes. Diabet Med, 2011. 28(8): p. 972-5.
6.Best CH, Ridout JH. “The Lipotropic Action of Methionine”. Journal of Physiology. 3 Oct 1939;97:489-494.
7.Artom C. “Mechanism of Action of Choline”. American Journal of clinical Nutrition
8.Gavin G, Patterson J, McHenry W. ” Comparison of the Lipotropic Effects of Choline, Inositol, and Lipocaic in Rats”. Journal of Biochemistry. 29 Jan 1943;148:275-279.
9.Solomon L. “Disorders of cobalamin (Vitamin B12) metabolism: Emerging concepts in pathophysiology, diagnosis and treatment”. Elsevier Review. pp. 1-15. Web.
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