Testosterone Cypionate / Testosterone Propionate Injection

Overview of Testosterone Cypionate / Testosterone Propionate Injection

Dosage Strength

Testosterone Cypionate / Testosterone Propionate 160/40 mg/mL 5 mL Vial (Grapeseed Oil)

General Information

The first anabolic steroid that was effectively produced was testosterone. A fast-acting, short-ester, oil-based testosterone injectable molecule called testosterone propionate is frequently administered to treat male hypogonadism, or low testosterone levels, and its numerous symptoms.

The purpose of testosterone propionate, which slows the release of synthetic testosterone into the bloodstream, was first described in 1935 to improve the therapeutic utility of the substance. Two years later, Schering AG in Germany made it available for therapeutic usage. It was sold under the trade name Testoviron and combined with testosterone enanthate. Prior to 1960, this type of testosterone dominated the market for prescription medications in the United States and was also the first one that was commercially available there.

The main androgen in the body is testosterone. Species of cells in the testis, ovary, and adrenal cortex produce endogenous testosterone. In the treatment of either congenital or acquired hypogonadism, testosterone is employed. The best exogenous androgen for the palliative therapy of breast cancer in postmenopausal women is testosterone. In 1938, testosterone was in use, and the FDA gave its approval in 1939. Since they have been used illegally, anabolic steroids, which are testosterone derivatives, are now considered controlled substances. In 1991, testosterone, along with a number of anabolic steroids, was designated as a restricted substance. Parenterally given dosages of both standard and delayed-release (depot) testosterone are available. The FDA initially approved testosterone transdermal patches (Androderm) in September 1995; today, there are numerous transdermal brands, forms, and products available, including implants, gels, and topical treatments. In July 2003, the FDA authorized the Striant testosterone buccal system. This mucoadhesive device clings to the buccal mucosa and offers a controlled and sustained release of testosterone. The FDA authorized an intranasal gel formulation in May 2014. (Natesto). The use of a transdermal patch (Intrinsa) for female hormone replacement is being studied; daily dosages are substantially lower for female users than for male users. The FDA decided to postpone the approval of the Intrinsa women’s testosterone patch in late 2004 and has since demanded more safety information, particularly in regards to cardiovascular and breast health.

The propionate ester is a type of chemical molecule that reacts with water to form alcohols and organic or inorganic acids. The majority of esters are made from carboxylic acids, and one or more esters are frequently supplied along with injectable testosterone. The testosterone molecule has an ester added to it, which affects how soluble it is after it enters the bloodstream. A large/long ester will have a longer half-life; the longer the carbon chain, the longer the ester, and the less soluble the drug. In contrast, short carbon chains, such as the propionate ester, act quickly on the body and expel waste products at a similar rate. The testosterone ester has the shortest half-life of all testosterone esters, at 4 days, thanks to its three-carbon chain.

References

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